More COVID-19 News: Israeli Scientists -- vaccine soon; distribution about 3 months away

[Sarcany]

Filliam H. Muffman wrote: Occasionally early releases of vaccines have killed people or made it more likely to get infected...

The first few Coronavirus vaccines (multiple teams working on these, notably one in China that promised a vaccine by mid-February) are likely to be of a new class, RNA vaccines.

The drug industry loves this class of vaccines. If you google it, you'll find lots of papers talking about the future of such vaccines. Very quick to design and easy to produce in great quantities.

This is the type you're going to hear about as "ready in weeks" because it can be engineered rapidly and governments dealing with panicky populations are going to waive regulations and testing and buy billions of dollars of anything that shows promise.

But there's no successful RNA vaccine.

It's new tech.

There's evidence that RNA vaccines may help with the course of a disease. But there's also evidence that the immune response from the vaccines they've trialed doesn't last beyond a few weeks or months.

There are problems with storage and transportation because they degrade rapidly if not chilled at precise temperatures. And there are problems with delivery-methods. These vaccines tend to be rejected by human cells, but in order to work they have to get into our cells to churn out proteins to stimulate the immune system, so they use nanoparticle delivery methods of a type which are usually held back for cancer chemo trials. The nanoparticles have their own problems with toxicology, weakening/crossing the blood-brain barrier, effects on liver and kidney function, etc.

Mosquirix is a mRNA vaccine against malaria. The WHO has been accused of using the populations of Malawi, Ghana, and Kenya for what amounts to a large-scale drug trial without informed consent. While the manufacturer promised long-term protection, there's evidence that the immune response from this vaccine fades in months. In the first few months of use it has been linked to higher rates of cerebral malaria (when parasite-infected blood cells block small blood vessels to the brain), and a two-fold risk of "all-cause mortality" in girls. Five other RNA drugs have been tested with similar negative outcomes.

I am big on vaccination. But not this way. You don't rush something like this out the door. It seems to me that pharmaceutical companies are taking advantage of the opportunity to enrich themselves selling miracle cures and snake oil.



(See my new post, below. Sept, 2020.)