Can regular headphones be used with Shuffle?

[Donkey Hotay]

If the headphones are 64 ohm impedance, then "no"
If the headphones are 36-40 ohm impedance, then "maybe yes"
If the headphones are 32 ohm impedance, then "yes"
If the headphones are 24-28 ohm impedance, then "maybe yes"
If the headphones are 16 ohm impedance, then "no"
If the headphones are 8 ohm impedance, then "no"
If the headphones are 4 ohm impedance, then "no"

You will have to get the technical specifications of the headphones from the manufacturer.

You want the impedance value to match the iPod's output circuitry as closely as possible.

I can't tell you "yes" or "no". You have neither specified the headphones by make and model number nor specified the headphone impedance value.